Chewing gum restores dad's taste and smell years after Covid
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TL;DR

A man who lost his taste and smell following COVID-19 has experienced significant recovery after chewing specially developed flavored gums during a 12-week trial. This development suggests potential new treatment avenues for post-COVID sensory impairments.

A man who lost his sense of taste and smell after contracting COVID-19 has reportedly regained both senses following a 12-week trial involving specially developed flavored chewing gums. This breakthrough could offer new hope for millions experiencing long-term sensory loss post-COVID, according to researchers at the University of Nottingham.

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Dr. Paul Wicks, a 44-year-old medical researcher from Staffordshire, participated in a clinical trial designed by Dr. Nicole Yang, which used flavored chewing gums to stimulate brain connections related to smell and taste. Wicks lost his senses in August 2022 and had not regained them until the trial.

The trial involved chewing specially formulated gums with different strong flavors—spicy, minty, sour, and sweet—twice daily for 12 weeks, similar to how sensory training is used in other therapies to stimulate neural pathways. Wicks noticed initial improvements after six weeks, including tasting blueberries and smelling familiar scents like coffee and his children’s hair. By the end of the trial, his senses were reportedly restored to pre-COVID levels.

Why It Matters

This development is significant because it suggests a non-invasive, at-home treatment option for long-term COVID-related sensory loss, which affects a substantial portion of COVID survivors. Restoring taste and smell can improve quality of life, emotional well-being, and the ability to form memories linked to sensory experiences.

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Background

Loss of taste and smell has been a common long-term symptom for some COVID-19 survivors, often persisting for months or years. Understanding sensory recovery can be crucial for developing effective treatments. Current treatments are limited, and recovery varies widely. For example, research into natural remedies like honey has shown some potential for sensory health which may inform future therapies. The University of Nottingham’s trial is among the first to explore sensory restoration through targeted sensory training using flavored gums, building on prior research into neural plasticity and sensory re-training.

“When I tasted blueberries again, it was like a flood of memories and sensations returning. It gave me hope that my senses could come back.”

— Dr. Paul Wicks

“Our trial shows that targeted sensory stimulation through flavored chewing gum can promote neural repair in the brain pathways responsible for smell and taste.”

— Dr. Nicole Yang

What Remains Unclear

It remains unclear whether this treatment is effective for all long-term COVID-19 sensory loss cases or only for certain individuals. The trial involved a small sample size, and larger studies are needed to confirm efficacy and safety.

What’s Next

Researchers at the University of Nottingham plan to seek funding for larger, more comprehensive trials to validate these initial findings. Further research will explore optimal formulations, duration, and potential for widespread clinical use, building on prior studies of sensory re-training and neural plasticity to enhance recovery strategies.

Key Questions

It is too early to say. The current trial involved a small group, and larger studies are needed to determine effectiveness across diverse populations.

How does the flavored chewing gum work to restore senses?

The gum is designed with strong, varied flavors that aim to stimulate neural pathways involved in taste and smell, encouraging brain plasticity and repair.

Is this treatment available now?

Not yet. The findings are preliminary, and further research and development are required before it becomes widely accessible.

How long does it take to see improvements?

Participants in the trial reported noticing changes after about six weeks of regular use, with full recovery by the end of 12 weeks.

Source: Hacker News

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